Hormone treatments

Find everything you need to know about hormone treatments for endometriosis


Hormone treatments aim to lower or block oestrogen, slowing the disease’s growth and easing symptoms. These treatments reduce endometriosis tissue growth but sometimes induce medical menopause due to their effect on the lining of the uterus.

Hormone effects are temporary and reverse once treatment stops. Your doctor should talk to you about the pros and cons of available hormone treatment options.

Combined Oral Contraceptive Pill (‘the Pill’)

Commonly known as ‘the Pill’, the combined oral contraceptive pill is often used in endometriosis treatment. It contains estrogen and progesterone, which can help regulate menstrual cycles, reduce menstrual flow and alleviate endometriosis pain.

Mirena Coil

The Mirena Coil is an intrauterine device (IUD) that releases the hormone progestin. It can reduce menstrual bleeding and relieve pain associated with endometriosis.


Progestogens are a type of hormone therapy used to treat endometriosis. They work by altering the hormone balance in the body, which can help reduce the growth of endometriosis tissue.

GnRH Analogues

GnRH (Gonadotropin-releasing hormone) is a medication that helps to manage endometriosis by reducing estrogen production. This reduction in estrogen can lead to a decrease in the growth of endometrial tissue.

Testosterone derivatives

Testosterone derivatives, such as Danazol, are sometimes used in the treatment of endometriosis. Danazol works by creating a high androgen (male hormone) and low estrogen environment, helping to reduce endometriosis symptoms.


Danazol is a synthetic androgen that can be effective in treating endometriosis. It is typically taken as a pill and can help reduce pain and shrink endometriosis implants.

Gestrinone (Dimetriose)

Gestrinone, also known as Dimetriose, is another type of hormone therapy used for endometriosis. Similar to Danazol, it works by altering the hormonal environment in the body.

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